Semaglutide
Once-weekly GLP-1 injection (or daily oral tablet) — the molecule that started this category.
How it works
Semaglutide is a GLP-1 receptor agonist — it mimics a natural gut hormone that slows stomach emptying, reduces appetite, and helps regulate blood sugar. It's the molecule that kicked off the modern GLP-1 weight-loss category, with the longest real-world track record of any drug in its class.
Who it's for
Adults looking to lose a meaningful amount of weight, especially those new to GLP-1 therapy or who prefer the most established option available. Also well suited to patients managing type 2 diabetes alongside their weight-loss goals.
Choose Your Dose
LIGHT. STANDARD. STRONG.
Pick the strength that matches your protocol. Each option takes you straight to that exact product's secure checkout.
A gentler introduction — well suited if you're new to GLP-1 therapy.
Continue to Checkout StandardOur most commonly prescribed strength for ongoing treatment.
Continue to Checkout StrongFor patients titrating toward a higher maintenance dose under physician guidance.
Continue to CheckoutA licensed physician reviews and confirms your protocol before anything ships.
Your Timeline
WHAT TO EXPECT
Weeks 1–4
Starter dose. Mild nausea or GI adjustment is common early on; appetite reduction often begins within the first couple of weeks.
Weeks 4–16
Your physician increases the dose on a clinically-guided schedule as you tolerate it, balancing appetite control against side effects.
Months 4–12
Most patients reach a maintenance dose in this window, with steady, sustained weight loss continuing.
Not appropriate for anyone with a personal or family history of medullary thyroid carcinoma or MEN-2, those who are pregnant or breastfeeding, or with active pancreatitis or severe gallbladder disease. Your intake and physician review screen for all of this before anything is prescribed.
Common Questions